FSH, or Follicle Stimulating Hormone used to be considered the “Gold Standard” in gauging a woman’s ovarian reserve – but no longer! AMH, or Antimullerian Hormone, is a more informative and better test than FSH by which to guage a woman’s ovarian reserve or predict successful outcome with fertility treatment.
An article published in Fertility and Sterility explains why AMH is truly a better test than FSH. Although FSH testing has been used since 1988 to assess ovarian reserve, clinicians have realized its limitations (like the fact that it can only be tested on the third day of a woman’s menstrual cycle).
AMH, on the other hand, has a number of benefits:
- AMH can be obtained at any point in the menstrual cycle
- It has age age-specific values and ranges
- AMH detects high ovarian reserve, which is a risk factor of hyperstimulation. (An AMH of 5 or higher is consistent with predisposition to hyperstimulation and polycystic ovaries.)
- AMH is an earlier marker of diminished ovarian reserve – a woman’s AMH levels will change before FSH goes up.
- AMH provides more information to the patient and the doctor regarding the current egg supply, and if you test it over time you get a better sense of rate of decline.