Endometriosis affects millions of women and is one of the most common causes of infertility. While many women with endometriosis can conceive naturally, others may need fertility treatment such as in vitro fertilization (IVF).
A recent peer-reviewed paper co-authored by Dr. Alex Kotlyar provides a contemporary review of how fertility specialists approach IVF in women with endometriosis — and what strategies may improve success rates.
Rather than presenting a single new study, this article carefully reviews the most current research and clinical evidence to help guide treatment decisions.
Here’s what patients should know.
How Does Endometriosis Affect Fertility?
Endometriosis occurs when tissue similar to the lining of the uterus grows outside the uterus. It can cause inflammation, scarring, ovarian cysts (called endometriomas), and changes in the pelvic environment.
In moderate to severe cases, endometriosis may:
- Lower ovarian reserve (fewer available eggs)
- Reduce the number of eggs retrieved during IVF
- Impact implantation rates
However, many women with endometriosis still have successful pregnancies — especially with individualized fertility care.
Key Insights From the Review
- Surgery Is Not Always the First Step
While surgery can help relieve pain, removing ovarian endometriomas before IVF does not always improve pregnancy rates and may reduce ovarian reserve. Current evidence supports a personalized approach rather than routine surgery before IVF.
- Individualized IVF Protocols Matter
Doctors may adjust stimulation medications, consider hormonal pretreatment, or recommend freezing embryos and transferring them in a later cycle. Frozen embryo transfer may help optimize the uterine environment for implantation in some patients.
- One Size Does Not Fit All
The review emphasizes tailoring treatment based on age, ovarian reserve, symptom severity, and reproductive goals.
The main takeaway: women with endometriosis can absolutely succeed with IVF — but treatment planning is especially important.
📄 You can read the full open-access article here:
Women with endometriosis who undergo IVF: a contemporary review of therapeutic strategies for successful outcomes
Frequently Asked Questions About Endometriosis and IVF
Does endometriosis mean I can’t get pregnant?
No. Many women with endometriosis conceive naturally. For others, IVF can be a highly effective treatment option.
Does endometriosis lower IVF success rates?
Women with moderate to severe endometriosis may produce fewer eggs and may have slightly lower pregnancy rates compared to women without endometriosis. However, many still achieve successful outcomes with the right treatment plan.
Should I remove an endometrioma before IVF?
Not necessarily. Surgery may sometimes reduce ovarian reserve. It is typically recommended only if the cyst is large, painful, suspicious in appearance, or interfering with egg retrieval.
Are there special IVF protocols for endometriosis?
Yes. Your doctor may adjust medications, consider pretreatment, or recommend frozen embryo transfer to improve implantation conditions.
What is the most important thing patients should know?
Endometriosis requires individualized care. Working with a fertility specialist experienced in treating endometriosis can make a significant difference.
If you would like to learn more about GENESIS Fertility New York or are ready to schedule an appointment, please speak with one of our representatives at 929-605-5467.
