When you’re trying to conceive, understanding whether your fallopian tubes are open is an important step. A new imaging procedure called hysterosalpingo-foam sonography (HyFoSy) has been gaining attention in fertility care—and recent clinical research confirms why. A recent, large-scale study reviewed all the current research on HyFosy to assess its effectiveness in comparison to older methods. The results are incredibly promising.

What Is HyFoSy?

HyFoSy (pronounced “hi-foh-see”) is a special ultrasound test used to check if the fallopian tubes are open. During the procedure, a doctor gently introduces a safe contrast foam into the uterus. The foam makes it easy to see whether the fluid passes through the fallopian tubes using ultrasound.

This helps fertility specialists quickly determine if there are blockages that could prevent pregnancy.

How Is HyFoSy Different From Other Tests?

All tubal patency tests have the same goal: to see if fluid can pass through your fallopian tubes. Traditionally, the two main options have been an X-ray test called HSG (hysterosalpingography) and, in some cases, a surgical procedure called a chromotubation via laparoscopy.

• HSG uses an X-ray and a fluid with iodine. It’s effective, but it can be painful, involves a small amount of radiation, and can cause allergic reactions.
• Laparoscopy with chromotubation is a surgical procedure. It’s the “gold standard” for accuracy but requires anesthesia and is invasive.
• HyFosy uses a simple ultrasound and a special gel mixed with water to create a stable foam. The doctor injects this foam and watches its path with an ultrasound. This means no X-rays, no surgery, and no iodine-based dyes.

What Did the New Research Show?

A recent study reviewed 20 different research papers to get a complete picture of how HyFosy performs. Here’s what they found:

• Just as Accurate as HSG: The study found that HyFosy is at least as effective as HSG at identifying whether your tubes are open. For many patients, the results were the same as those from a surgical laparoscopy, which is considered the most accurate method. HyFosy had the same result as laparoscopy in 94% of patients.
• Less Painful: This is a big one. Patients reported significantly less pain with HyFosy compared to HSG. In fact, 95% of patients in the studies reported mild to no pain during the procedure.
• Extremely Low Risk: The procedure has a very low risk of failure or side effects. The study found that only 1% of patients experienced a procedure failure or a side effect after a HyFosy.
• The Big Advantage: During a single HyFosy procedure, a doctor can assess not only your fallopian tubes but also your uterus and ovaries. This is a huge time-saver compared to HSG, which often requires a separate ultrasound to examine other parts of your reproductive system.

In other words, HyFoSy gives doctors the information they need while making the experience easier for patients.

Why This Matters for Fertility Patients

When you’re going through fertility testing, every step can feel overwhelming. Having an option that is accurate, safe, and more comfortable is a real advantage. HyFoSy helps your doctor get a clear picture of your fertility health, so you can move forward with the right treatment plan.

What to Expect If You Have a HyFoSy Fertility Test

• The procedure is usually done in your fertility clinic.
• You may feel mild cramping, but most patients tolerate it well.
• You can typically return to normal activities right after the test.

Your doctor will review the results with you immediately and explain what they mean for your fertility journey.

Frequently Asked Questions About HyFoSy

Is HyFoSy painful?
Most patients describe the procedure as mildly uncomfortable, with some cramping similar to menstrual cramps. It is usually less painful than an HSG.

How long does the HyFoSy test take?
The test typically takes 15–30 minutes, and you can return to normal activities right afterward.

When is the best time to schedule HyFoSy?
Doctors usually perform the test after your period but before ovulation (early in your cycle). This timing ensures the uterus lining is thin and you’re not pregnant.

Are there any risks with HyFoSy?
HyFoSy is considered very safe. Side effects are rare but may include temporary cramping, spotting, or mild discomfort.

Does HyFoSy improve fertility?
HyFoSy is mainly a diagnostic test, but some patients report becoming pregnant shortly afterward—possibly because the procedure may help clear debris in the fallopian tubes.

HyFoSy at Genesis Fertility

If you’re preparing for fertility treatment or just beginning your journey, our clinic is proud to offer the HyFoSy fertility test. This safe, accurate, and gentle procedure helps us give you the answers you need so we can create the best plan for your path to parenthood.